AKT-IN-25

MedChem Express

AKT-IN-25

5

Research Use Only

AKT-IN-25 (Compound 14a) is an inhibitor for Akt , that inhibits the phosphorylation of Akt, and thereby inhibits the PI3K/Akt/mTOR signaling pathway. AKT-IN-25 arrests the cell cycle at G1 phase, inhibits the cell migration of PANC-1, and inhibits the proliferation of cancer cells PANC-1, PATU-T, and SUIT-2 with IC 50 s of 3.05, 1.32, and 3.85 microM, respectively [1] .

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