Akt1/Akt2-IN-2

MedChem Express

Akt1/Akt2-IN-2

5

Research Use Only

98.57

C40H43N7O2

653.82

Akt1/Akt2-IN-2 (compound 7) is an allosteric dual Akt1 and Akt2 inhibitor ( IC 50 =138 nM and 212 nM, respectively). Akt1/Akt2-IN-2 increases activity of caspase-3, and inhibits viability of a number of tumor cells [1] .

O=C(C1=CC=C2N=C(C3=CC=CC=C3)C(C4=CC=C(CN5CCC(N6C7=CC=CC=C7NC6=O)CC5)C=C4)=NC2=C1)NCCN(CC)CC

-20°C,2°C to 8°C

12352200