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AL 8697

HY-108645
MedChem Express
CAS Number1057394-06-5
DownloadMSDS
Product group Chemicals
Estimated Purity99.83
Molecular Weight402.41
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Overview

  • Supplier
    MedChem Express
  • Product Name
    AL 8697 [1057394-06-5]
  • Delivery Days Customer
    10
  • CAS Number
    1057394-06-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.83
  • Molecular Formula
    C21H21F3N4O
  • Molecular Weight
    402.41
  • Scientific Description
    AL 8697 is a specific and orally active p38alpha MAPK inhibitor with an IC 50 of 6 nM. AL 8697 displays 14-fold greater inhibition of p38alpha compared to p38beta ( IC 50 =82 nM), and 300-fold selectivity for p38alpha over a panel of 91 kinases. Anti-inflammatory activity [1] .
  • SMILES
    O=C(NC1CC1)C2=CC(F)=C(C)C(C3=C(F)C4=NN=C(C(C)(C)C)N4C=C3F)=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200