ALAS1 Polyclonal Antibody
RD81425A
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetALAS1
Overview
- SupplierReddot Biotech
- Product NameALAS1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID211
- Target nameALAS1
- Target description5'-aminolevulinate synthase 1
- Target synonyms5-aminolevulinate synthase, nonspecific, mitochondrial; 5-aminolevulinic acid synthase 1; ALAS; ALAS3; ALASH; ALAS-H; aminolevulinate, delta-, synthase 1; delta-ALA synthase 1; delta-aminolevulinate synthase 1; MIG4; migration-inducing protein 4
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203