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AlbA-DCA

T13538
TargetMol Chemicals
Molecular Weight860.9
Product group Chemicals
Price on request
Packing Size
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    AlbA-DCA
  • Delivery Days Customer
    999
  • Category Supplier
    Chemical
  • Chemical Name
    AlbA-DCA
  • Molecular Formula
    C43H67Cl2NO12
  • Molecular Weight
    860.9
  • Scientific Description
    AlbA-DCA is a conjugate formed by the attachment of Albiziabioside A to a dichloroacetate acid subunit. It can induce a marked increase in intracellular ROS and alleviate the accumulation of lactic acid in the tumor microenvironment, and also selectively kills cancer cells and induce apoptosis.
  • Shelf life instruction
    3 years
  • SMILES
    O[C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)NC(C(Cl)Cl)=O)O[C@H]2CC[C@]3(C(C2(C)C)CC[C@@]4(C3CC=C5[C@]4(CC[C@@]6(C5CC(C)(CC6)C)C(O)=O)C)C)C)CO[C@@H]7OC[C@@H]([C@@H]([C@H]7O)O)O
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Wei G, et al. Natural Product Albiziabioside A Conjugated with Pyruvate Dehydrogenase Kinase Inhibitor Dichloroacetate To Induce Apoptosis-Ferroptosis-M2-TAMs Polarization for Combined Cancer Therapy. J Med Chem. 2019 Oct 10;62(19):8760-8772.
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