ALDH2 ELISA Pair

GeneTex

ALDH2 ELISA Pair

9

We recommend using the capture antibody at a concentration of 2.5microg/mL and the detection antibody at a concentration of 1.5microg/mL. Optimal dilutions should be determined experimentally by the researcher.

ELISA

Research Use Only

ALDH2

aldehyde dehydrogenase 2 family member

ALDH-E2, ALDHI, ALDM, aldehyde dehydrogenase, mitochondrial, ALDH class 2, acetaldehyde dehydrogenase 2, aldehyde dehydrogenase 2 family (mitochondrial), epididymis secretory sperm binding protein, liver mitochondrial ALDH, nucleus-encoded mitochondrial aldehyde dehydrogenase 2

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203