Bio-Connect

ALK Monoclonal Antibody

RD6910R
Reddot Biotech
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetALK
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    ALK Monoclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Concentration
    100 ug/ml
  • Gene ID238
  • Target name
    ALK
  • Target description
    ALK receptor tyrosine kinase
  • Target synonyms
    ALK tyrosine kinase receptor; anaplastic lymphoma receptor tyrosine kinase; CD246; CD246 antigen; mutant anaplastic lymphoma kinase; NBLST3
  • Host
    Rabbit
  • Scientific Description
    ALK (Anaplastic Lymphoma Kinase, cd246) is a transmembrane receptor of leucine kinase with molecular weight about 200 kDa. ALK gene was found in CD30 + anaplastic large cell lymphoma cases in 1980. If there is genetic translocation, tumor cells will produce a kind of NPM-ALK heterozygous protein (also known as p80). In normal tissues, a few cells express ALK, such as glial cells, neurons and so on. In tumor cases, literature has shown that ALK is expressed in anaplastic large cell lymphoma, inflammatory myofibroblastic tumor, rhabdomyosarcoma, leiomyoma and lung adenocarcinoma.
  • UNSPSC
    12352203