ALK5-IN-31

MedChem Express

ALK5-IN-31

10

Research Use Only

C23H23FN8

430.48

ALK5-IN-31 (compound Ex-08) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-beta-induced SMAD signaling. ALK5-IN-31 has the potential to inhibit growth of tumour in vivo. ALK5-IN-31 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1].

CC1=CC=CC2=C(NC3=NC(NC4=CC=C(N5CCNCC5)C(F)=C4)=NC=C3)C=NN=C12

12352200