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Almorexant (hydrochloride)

HY-10805A
MedChem Express
CAS Number913358-93-7
DownloadMSDS
Product group Chemicals
Estimated Purity99.98
Molecular Weight549.02
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Almorexant (hydrochloride) [913358-93-7]
  • Delivery Days Customer
    5
  • CAS Number
    913358-93-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.98
  • Molecular Formula
    C29H32ClF3N2O3
  • Molecular Weight
    549.02
  • Scientific Description
    Almorexant (ACT 078573) hydrochloride is an orally active, potent and competitive dual orexin receptor antagonist, with K d values of 1.3 nM ( OX1 ) and 0.17 nM ( OX2 ), respectively. Almorexant hydrochloride reversibly blocks signaling of orexin-A and orexin-B peptides. Almorexant hydrochloride totally blocked the intracellular Ca 2+ signal pathway. Almorexant hydrochloride stimulates caspase-3 activity in AsPC-1 cells and induces apoptosis [1] [2] [3] [4] .
  • SMILES
    CNC([C@@H](C1=CC=CC=C1)N2CCC3=CC(OC)=C(OC)C=C3[C@@H]2CCC4=CC=C(C(F)(F)F)C=C4)=O.Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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