Alosetron (Hydrochloride) (Standard) [122852-69-1]
HY-70050CR
Product group Assays
Overview
- SupplierMedChem Express
- Product NameAlosetron (Hydrochloride) (Standard) [122852-69-1]
- Delivery Days Customer5
- CAS Number122852-69-1
- CertificationResearch Use Only
- Molecular FormulaC17H19ClN4O
- Molecular Weight330.81
- Scientific DescriptionAlosetron (Hydrochloride) (Standard) is the analytical standard of Alosetron (Hydrochloride). This product is intended for research and analytical applications. Alosetron Hydrochloride (GR 68755C) is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron Hydrochloride is used for the research of irritable bowel syndrome (IBS). Alosetron blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC50 at ~55 nM. Alosetron Hydrochloride attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects[1][2].
- SMILESO=C(C(C1=C2C=CC=C1)=C(N2C)CC3)N3CC4=C(NC=N4)C.[H]Cl
- UNSPSC41116135