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ProductsBack/Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker) (AACT/1452), CF640R conjugate, 0.1mg/mL [26628-22-8]

Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker) (AACT/1452), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC401452
Biotium
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetSERPINA3
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Overview

  • Supplier
    Biotium
  • Product Name
    Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker) (AACT/1452), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    AACT/1452
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID12
  • Target name
    SERPINA3
  • Target description
    serpin family A member 3
  • Target synonyms
    AACT; ACT; alpha-1-antichymotrypsin; cell growth-inhibiting gene 24/25 protein; GIG24; GIG25; growth-inhibiting protein 24; growth-inhibiting protein 25; serine (or cysteine) proteinase inhibitor, clade A, member 3; serpin A3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP01011
  • Protein Name
    Alpha-1-antichymotrypsin
  • Scientific Description
    Alpha-1 Antichymotrypsin (AACT) is a plasma protease inhibitor synthesized in the liver as a single glycopeptide chain. In human, the normal serum level of AACT is about one-tenth that of alpha-1-antitrypsin (AAT), with which it shares nucleic acid and protein sequence homology. Both are major acute phase reactants; their concentrations in plasma increase in response to trauma, surgery and infection. Elevated levels of AACT are widely, but not universally, reported in the cerebrospinal fluid and plasma of AD patients. Prostate-specific antigen (PSA) and its SDS-stable complex with AACT are in widespread use as markers for the diagnosis of prostate cancer. AACT deficiency may also be a possible cause of chronic liver disease. AACT antibody reacts with histiocytes and histiocytic neoplasms. It is widely used to identify histiocytes and tumors derived from them. Acinar tumors of the pancreas and salivary gland may also exhibit AACT positivity.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203