
ICC/IF analysis of NRK cells using GTX40044 alpha 1,2 Mannosidase IA antibody at 10 microg/mL. Cells were fixed and permeabilized with cold methanol followed by cold methanol:acetone (1:1).
alpha 1,2 Mannosidase IA antibody
GTX40044
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMAN1A1
Overview
- SupplierGeneTex
- Product Namealpha 1,2 Mannosidase IA antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 0.5-1 microg/ml. ICC/IF: 5-10 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4121
- Target nameMAN1A1
- Target descriptionmannosidase alpha class 1A member 1
- Target synonymsalpha-1,2-mannosidase IA; HUMM3; HUMM9; man(9)-alpha-mannosidase; MAN9; Man9-mannosidase; mannosyl-oligosaccharide 1,2-alpha-mannosidase IA; processing alpha-1,2-mannosidase IA
- HostRabbit
- IsotypeIgG
- Protein IDP33908
- Protein NameMannosyl-oligosaccharide 1,2-alpha-mannosidase IA
- Scientific DescriptionAlpha 1,2-Mannosidase IA is a Type II transmembrane Golgi-resident enzyme that belongs to class I alpha 1,2- Mannosidases (glycosylhydrolase family 47). Alpha 1,2-Mannosidases play an essential role in the maturation of N-glycans to hybrid and complex oligosaccharides in mammalian cells. They can be classified into three subgroups according to their enzymatic activities. The second subgroup includes mammalian Golgi alpha 1,2-Mannosidases IA, IB, and IC. It has been suggested that Golgi mannosidases from this subgroup may play a role in the ERAD (endoplasmic reticulum-associated degradation) of defective glycoproteins.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203