Alpha, Beta - Synuclein antibody [3B6]

GeneTex

Alpha, Beta - Synuclein antibody [3B6]

9

We recommend the following starting dilutions:Western Blot: Use at 1:1,000 ~ 2,000.Optimal working concentrations should be determined experimentally by the end user.

Western Blot, ELISA

Research Use Only

Monoclonal

3B6

1 mg/ml

Unconjugated

Liquid

SNCA

synuclein alpha

alpha-synuclein; I+/--synuclein; NACP; non A-beta component of AD amyloid; PARK1; PARK4; PD1; synuclein alpha-140; synuclein, alpha (non A4 component of amyloid precursor); truncated alpha synuclein

Mouse

IgG1

alpha-synuclein (amino acids 119-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinsons disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Specially, the non-A? component of amyloid plaques is a highly amyloidogenic peptide consisting of 35 amino acids which was first identified associated with senile plaques in the Alzheimers disease brain.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203