alpha-Conotoxin BuIA
HY-P5148
Molecular Weight1311.57
Product group Chemicals
Overview
- SupplierMedChem Express
- Product Namealpha-Conotoxin BuIA
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC54H82N14O16S4
- Molecular Weight1311.57
- Scientific Descriptionalpha-Conotoxin BuIA is a paralytic peptide neurotoxin and a competitive nAChR antagonist, with IC50s of 0.258 nM (alpha6/alpha3beta2), 1.54 nM (alpha6/alpha3beta4), 5.72 nM (alpha3beta2), respectively. alpha-Conotoxin BuIA can be used to distinguish nAChRs containing beta2- and beta4-subunit, respectively. alpha-Conotoxin BuIA distinguishes among alphaxbeta2 nAChRs with a rank order potency of alpha6>alpha3>alpha2>alpha4[1].
- SMILESO=C(CN)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N2[C@H]3CCC2)=O)CCC1)=O)[C@@H](C)O)=O)CO)=O)CSSC[C@H](NC4=O)C(N)=O)=O)CSSC[C@H](NC3=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]4CC5=CC=C(O)C=C5)=O)CC(C)C)=O)C(C)C)=O)C)=O
- UNSPSC12352200