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alpha-Conotoxin GID

Research Use Only
HY-P5147
MedChem Express
Molecular Weight2186.39
Product group Chemicals
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    alpha-Conotoxin GID
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Molecular Formula
    C84H132N30O31S4
  • Molecular Weight
    2186.39
  • Scientific Description
    alpha-Conotoxin GID is a paralytic peptide neurotoxin and a selective antagonist of nAChR, with IC50s of 5 nM (alpha7), 3 nM (alpha3beta2), 150 nM (alpha4beta2), respectively. alpha-Conotoxin GID is small disulfide-rich peptide, with potential to inhibit chronic pain. alpha-Conotoxin GID contains a C-terminal carboxylate, thus substitution with a C-terminal carboxamide results in loss of alpha4beta2 nAChR. alpha-Conotoxin GID can be isolated from the Conus species[1][2][3].
  • SMILES
    O=C1[C@@]2([H])N(C[C@@H](C2)O)C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@]3([H])NC([C@@H](NC([C@@]4([H])N(CCC4)C([C@@H](NC([C@@H](NC([C@](NC([C@H](CSSC3)NC([C@H](CC(C(O)=O)C(O)=O)NC([C@H](CC(O)=O)NC([C@H](CCCNC(N)=N)NC([C@@H](N)[C@@H](C)CC)=O)=O)=O)=O)
  • UNSPSC
    12352200