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IHC-P analysis of human heart tissue using GTX11302 alpha Tubulin antibody [DM1A] at 1:500.
IHC-P analysis of human heart tissue using GTX11302 alpha Tubulin antibody [DM1A] at 1:500.
IHC-P analysis of human heart tissue using GTX11302 alpha Tubulin antibody [DM1A] at 1:500.

alpha Tubulin antibody [DM1A]

GTX11302
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Chicken, Fungus, Human, Monkey, Mouse, Rat, Yeast
TargetTUBA8A
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Overview

  • Supplier
    GeneTex
  • Product Name
    alpha Tubulin antibody [DM1A]
  • Delivery Days Customer
    9
  • Antibody Specificity
    The antibody is specific for α-tubulin in immunoblotting assays and may be used for localization of α-tubulin in cultured cells or tissue sections. The antibody reacts best with chicken fibroblasts.
  • Application Supplier Note
    WB: 1:500. ICC/IF: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    DM1A
  • Conjugate
    Unconjugated
  • Gene ID418166
  • Target name
    TUBA8A
  • Target description
    tubulin alpha 8A
  • Target synonyms
    alpha 4 tubulin; TUBA4A; TUBA8; tubulin alpha-4 chain; tubulin, alpha 4a; tubulin, alpha 8
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    Tubulin is the major building block of microtubules. This intracellular cylindrical filamentous structure is present in almost all eukaryotic cells. Microtubules function as structural and mobile elements in mitosis, intracellular transport, flagellar movement and in the cytoskeleton. Tubulin is a heterodimer which consists of alpha-tubulin and beta-tubulin; both subunits have a molecular weight of approximately 50 kDa and share considerable homology. The most widely studied tubulins have been isolated from vertebrate brains. The microtubules can be viewed in immunofluorescent microscopy, which enables the observation of the intracellular organization of proteins that are in the form of a supramolecular structure.GT211302 may be used to study the intracellular organization and distribution of tubulin along the static and dynamic aspects of the cytoskeleton. The product can be used for the immunocytochemical localization of the alpha chain of tubulin by means of indirect immunofluorescent labeling of cultured cells, formalin fixed or frozen tissues or for specific identification of the alpha-tubulin band in immunoblotting or immunoprecipitation techniques.
  • Reactivity
    Bovine, Canine, Chicken, Fungus, Human, Monkey, Mouse, Rat, Yeast
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • BAF facilitates interphase nuclear membrane repair through recruitment of nuclear transmembrane proteins. Young AM et al., 2020 Jul 15, Mol Biol Cell
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  • PGRMC2 is an intracellular haem chaperone critical for adipocyte function. Galmozzi A et al., 2019 Dec, Nature
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  • NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase. Hsieh YL et al., 2019 Nov 19, Cell Rep
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  • Dengue virus-elicited tryptase induces endothelial permeability and shock. Rathore AP et al., 2019 Jul 2, J Clin Invest
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  • Targeting PKCdelta as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung Cancer. Lee PC et al., 2018 Dec 10, Cancer Cell
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  • HSPB7 is indispensable for heart development by modulating actin filament assembly. Wu T et al., 2017 Nov 7, Proc Natl Acad Sci U S A
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  • Proteome analysis of irradiated endothelial cells reveals persistent alteration in protein degradation and the RhoGDI and NO signalling pathways.
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  • Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via beta-hydroxybutyrate. Huang CK et al., 2017 Mar 10, Nat Commun
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  • Low-dose radiation differentially regulates protein acetylation and histone deacetylase expression in human coronary artery endothelial cells.
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