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ProductsBack/alpha7 nAchR-JAK2-STAT3 agonist 1

alpha7 nAchR-JAK2-STAT3 agonist 1

Research Use Only
HY-146066
MedChem Express
Molecular Weight426.50
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Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    alpha7 nAchR-JAK2-STAT3 agonist 1
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C25H30O6
  • Molecular Weight
    426.50
  • Scientific Description
    alpha7 nAchR-JAK2-STAT3 agonist 1 is a potent alpha7 nAchR-JAK2-STAT3 agonist, with an IC50 value of 0.32 microM for nitric oxide (NO). alpha7 nAchR-JAK2-STAT3 agonist 1 effectively suppresses the expression of iNOS, IL-1beta, and IL-6 in murine RAW264.7 macrophages. alpha7 nAchR-JAK2-STAT3 agonist 1 can inhibit LPS-induced NO release, NF-kappaB activation and cytokine production. alpha7 nAchR-JAK2-STAT3 can be used for researching sepsis[1].
  • SMILES
    O=C(O[C@@H](CCCCC1=CC=CC=C1)CCC2=CC=C(OC(C)=O)C(OC(C)=O)=C2)C
  • UNSPSC
    12352200