ALX4 antibody [KAB4]

GeneTex

ALX4 antibody [KAB4]

9

WB: Use at a concentration of 1 - 5 microg/ml. Detects bands of approximately 41 and 43 kDa. Optimal dilutions/concentrations should be determined by the end user.

Western Blot

Research Use Only

Monoclonal

KAB4

1 mg/ml

Unconjugated

ALX4

ALX homeobox 4

aristaless-like homeobox 4; CRS5; FND2; homeobox protein aristaless-like 4; homeodomain transcription factor ALX4

Mouse

IgG1

Homeobox protein aristaless-like 4

This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, cognitive disability, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq, Oct 2009]

Human

-20°C or -80°C,2°C to 8°C

12352203