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AM-2394 [1442684-77-6]

AM-2394 [1442684-77-6]

T3312
TargetMol Chemicals
CAS Number1442684-77-6
Product group Chemicals
Estimated Purity99.58%
Molecular Weight423.46
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    AM-2394 [1442684-77-6]
  • Delivery Days Customer
    9
  • CAS Number
    1442684-77-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    AM-2394
  • Estimated Purity
    99.58%
  • Molecular Formula
    C22H25N5O4
  • Molecular Weight
    423.46
  • Scientific Description
    AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the phosphorylation of glucose to glucose-6-phosphate. AM-2394(AM2394) increases the affinity of GK for glucose by approximately 10-fold, exhibits moderate clearance and good oral bioavailability in multiple animal models, and lowers glucose excursion following an oral glucose tolerance test in an ob/ob mouse model of diabetes.
  • Shelf life instruction
    3 years
  • SMILES
    CNC(=O)Nc1cc(Oc2cncc(C)c2)c(cn1)-c1ccc(OCC(C)(C)O)nc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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