AMACR Polyclonal Antibody

Reddot Biotech

AMACR Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

AMACR

alpha-methylacyl-CoA racemase

2-methylacyl-CoA racemase; alpha-methylacyl-CoA racemase; AMACRD; CBAS4; P504S; RACE; RM

Rabbit

IgG

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

Human, Mouse, Rat

-20°C

12352203