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Amantadine Hydrochloride [665-66-7]

Research Use Only
A4802
LKT Laboratories
Product group Chemicals
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Amantadine Hydrochloride [665-66-7]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Scientific Description
    Viral M2 proton channel blocker, MAO-A, NET, NMDA, alfa7 nAChR antagonist.; Amazolon, Mantadan, Mantadine, Symmetrel, Vitrofral
  • UNSPSC
    12352200

References

  • Sommerauer C, Rebernik P, Reither H, et al. The noradrenaline transporter as site of action for the anti-Parkinson drug amantadine. Neuropharmacology. 2012 Mar;62(4):1708-16. PMID: 22155208. Jing X, Ma C, Ohigashi Y, et al. Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10967-72. PMID: 18669647. Blanpied TA, Clarke RJ, Johnson JW. Amantadine inhibits NMDA receptors by accelerating channel closure during channel block. J Neurosci. 2005 Mar 30;25(13):3312-22. PMID: 15800186. Pearce J. Mechanism of action of amantadine. Br Med J. 1971 Aug 26;3(5773):529. PMID: 4327681.