Amantadine Hydrochloride [665-66-7]
A4802
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameAmantadine Hydrochloride [665-66-7]
- Delivery Days Customer7
- CertificationResearch Use Only
- Scientific DescriptionViral M2 proton channel blocker, MAO-A, NET, NMDA, alfa7 nAChR antagonist.; Amazolon, Mantadan, Mantadine, Symmetrel, Vitrofral
- UNSPSC12352200
References
- Sommerauer C, Rebernik P, Reither H, et al. The noradrenaline transporter as site of action for the anti-Parkinson drug amantadine. Neuropharmacology. 2012 Mar;62(4):1708-16. PMID: 22155208. Jing X, Ma C, Ohigashi Y, et al. Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10967-72. PMID: 18669647. Blanpied TA, Clarke RJ, Johnson JW. Amantadine inhibits NMDA receptors by accelerating channel closure during channel block. J Neurosci. 2005 Mar 30;25(13):3312-22. PMID: 15800186. Pearce J. Mechanism of action of amantadine. Br Med J. 1971 Aug 26;3(5773):529. PMID: 4327681.