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AMD3465 hexahydrobromide (AMD3465 )

M2381
AbMole BioScience
CAS Number185991-07-5
Product group Chemicals
Estimated Purity>98.0%
Molecular Weight896.07
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    AMD3465 hexahydrobromide (AMD3465 )
  • Delivery Days Customer
    9
  • CAS Number
    185991-07-5
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    >98.0%
  • Molecular Formula
    C24H38N6.6HBr
  • Molecular Weight
    896.07
  • Scientific Description
    AMD3465 hexahydrobromide(AMD3465 ) is an effective CXCR4 antagonist that inhibits 12G5 mAb in SupT1 cells. The IC50 values of CXCL12AF647 and CXCR4 were 0.75 nM and 18 nM, respectively. AMD 3465 also effectively inhibited X4 HIV replication (IC50, 1-10 nM), but not R5 HIV replication.
  • SMILES
    2-Pyridinemethanamine, N-[[4-(1,4,8,11-tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-, hydrobromide (1:6)
  • UNSPSC
    12352200

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