Amelparib

MedChem Express

Amelparib

5

Research Use Only

99.17

C19H25N3O3

343.42

Amelparib (JPI-289 free base) is a potent, orally active, and water-soluble inhibitor of PARP-1. Amelparib inhibits PARP-1 activity (IC50=18.5 nM) and cellular PAR formation (IC50=10.7 nM) in the nanomolar range. Amelparib is a potential neuroprotective agent. Amelparib has the potential for the research of acute ischaemic stroke[1].

O=C1C2=C(C3=C(C=C(C=C3N1)CN4CCOCC4)OCC)NCCC2

-20°C,2°C to 8°C

12352200