AMG-076

MedChem Express

AMG-076

14

Research Use Only

C32H39F3N2O5S

620.72

AMG-076 is an orally bioavailable and selective MCHR1 antagonist. AMG-076 results in significant reduction in body weight gain in nonobese mice fed a high-fat diet and in high-fat diet-induced obese (DIO) mice [1] .

O=C(O)C1(CCCCC1)CCN2CC[C@@]3(CC4=C([C@@H]([C@]3(C2)[H])C)C(C=C(C=C5)C(F)(F)F)=C5N4)[H].O=S(C6=CC=CC=C6)(O)=O

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