AMG-193
E1600
Estimated Purity...
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameAMG-193
- Delivery Days Customer9
- CertificationResearch Use Only
- Estimated Purity...
- Scientific DescriptionAMG-193 is an orally active and MTA-cooperative inhibitor of PRMT5 with potent biochemical and cellular activity. AMG-193, in combination with MTA, selectively targets and inhibits the growth of MTAP-deficient tumor cells by suppressing PRMT5, with an IC50 of 0.107 microM, while sparing normal cells that possess wild-type MTAP. AMG-193 also exhibits antitumor activity.
- UNSPSC51202000