AMG-222

MedChem Express

AMG-222

9

Research Use Only

C32H39N9O3

597.71

AMG-222 is a dipeptidyl peptidase IV ( DPP-IV ) inhibitor that exerts its inhibitory effect by tightly and reversibly binding to DPPIV . AMG 222 binds to human plasma proteins in a saturable and concentration-dependent manner, with a binding rate of 80.8% at 1 nM, while the binding rate decreases to 29.4% at concentrations above 100 nM. AMG-222 can be used in research related to diabetes [1] .

O=C(C1=CC=C(C(C2=NNN=N2)(C[C@@H](NCC(N3[C@H](C#N)CCC3)=O)C)C4=CC=C(C(N(C)C)=O)C=C4CC5)C5=C1)N(C)C

12352200