AMG 232 ( KRT-232 )

Selleck Chemicals

AMG 232 ( KRT-232 ) [1352066-68-2]

9

Research Use Only

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AMG 232 (Navtemadlin) is a potential, selective inhibitor of the MDM2-p53 interaction, with an IC50 of 0.6 nM and binds to MDM2 with a Kd of 0.045 nM. It also demonstrated antitumor activity in vivo in a variety of tumor types with different genetic backgrounds.

51202000