AMG-47a

Biorbyt

AMG-47a [882663-88-9]

16

882663-88-9

C29H28F3N5O2

535.5601

AMG-47a is a potent inhibitor of Lck and T cell proliferation; exhibits anti-inflammatory activity (ED50 = 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice.

FC(C1C([H])=C([H])C([H])=C(C=1[H])N([H])C(C1C([H])=C([H])C(C([H])([H])[H])=C(C=1[H])C1C([H])=C([H])C2C(=C([H])N=C(N=2)N([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C=1[H])=O)(F)F

12352200