AMG 900

Biorbyt

AMG 900 [945595-80-2]

16

945595-80-2

Research Use Only

C28H21N7OS

503.57764

AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM; > 10-fold selective for Aurora kinases than p38alpha, Tyk2, JNK2, Met and Tie2.

CC1=CSC(C2=NN=C(C3=C2C=CC=C3)NC4=CC=C(C=C4)OC5=C(C=CC=N5)C6=CC=NC(N)=N6)=C1

12352200