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ProductsBack/Amidepsine D [79786-34-8]
Chemical Structure
Chemical Structure
Chemical Structure

Amidepsine D [79786-34-8]

Research Use Only
AG-CN2-0110
AdipoGen Life Sciences
CAS Number79786-34-8
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Product group Chemicals
Estimated Purity>95%
Molecular Weight496.5
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Amidepsine D [79786-34-8]
  • Delivery Days Customer
    10
  • CAS Number
    79786-34-8
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Warning
  • Molecular Formula
    C26H24O10
  • Molecular Weight
    496.5
  • Scientific Description
    Chemical. CAS: 79786-34-8. Formula: C26H24O10. MW: 496.5. Isolated from Humcola sp. FO-2942. Diacylglycerol acyltransferase (DGAT) inhibitor. Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders. - Diacylglycerol acyltransferase (DGAT) inhibitor [1-4]. Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
  • SMILES
    COC1=CC(OC)=C(C(=O)OC2=CC(C)=C(C(=O)OC3=CC(C)=C(C(O)=O)C(O)=C3)C(O)=C2)C(C)=C1
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties: H. Tomoda, et al.; J. Antibiot. 48, 937 (1995)
  • Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. II. Structure elucidation of amidepsines A, B and C: H. Tomoda, et al.; J. Antibiot. 48, 942 (1995)
  • Amidepsine E, an inhibitor of diacylglycerol acyltransferase produced by Humicola sp. FO-5969: H. Tomoda, et al.; J. Antibiot. 49, 929 (1996)
  • Potential therapeutics for obesity and atherosclerosis: inhibitors of neutral lipid metabolism from microorganisms: H. Tomoda & S. Omura; Pharmacol. Ther. 115, 375 (2007)