(-)-Amosulalol

MedChem Express

(-)-Amosulalol

9

Research Use Only

C18H24N2O5S

380.46

(-)-Amosulalol ((-)-YM 09538) is an isomer of Amosulalol (HY-106720), an orally active dual inhibitor of alpha1/beta1-adrenergic receptors. Amosulalol exhibits antihypertensive activity by inhibiting alpha1-adrenergic receptors. Amosulalol reduces the reflex increase in heart rate and plasma renin activity (PRA) in spontaneously hypertensive rats (SHR) by inhibiting beta1-adrenergic receptors.

O=S(C1=CC([C@@H](O)CNCCOC2=CC=CC=C2OC)=CC=C1C)(N)=O

12352200