AMPK alpha2 Polyclonal Antibody

Reddot Biotech

AMPK alpha2 Polyclonal Antibody

5

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Prkaa2

protein kinase AMP-activated catalytic subunit alpha 2

5'-AMP-activated protein kinase catalytic subunit alpha-2; ACACA kinase; acetyl-CoA carboxylase kinase; AMP-activated protein kinase; Ampk; AMPK alpha-2 chain; AMPK subunit alpha-2; Ampka2; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; protein kinase, AMP-activated, alpha 2 catalytic subunit

Rabbit

IgG

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

Human, Rat

-20°C

12352203