Amyloid 17-42 [155178-13-5]

TargetMol Chemicals

Amyloid 17-42 [155178-13-5]

999

Chemical

Research Use Only

Amyloid 17-42

C119H194N28O33S

2577.05

Amyloid 17-42 (Abeta(17-42)), a significant component of diffuse plaques in Alzheimers disease and cerebellar pre-amyloid in Downs syndrome, results from alpha- and gamma-secretase cleavage of amyloid precursor protein (APP) and can trigger neuronal apoptosis via the Fas-like/caspase-8 activation pathway [1].

3 years

[C@H](CC1=CC=CC=C1)(C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)[C@H](CC)C)=O)[C@H](C)C)=O)C(C)C)=O)=O)=O)[C@@H](C)C)=O)CCSC)=O)CC(C)C)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)C)=O)=O)CCCCN)=O)CC(N)=O)=O)CO)=O)=O)[C@@H](C)C)=O)CC(O)=O)=O)CCC(O)=O)=O)C)=O)=O)NC([C@@H](NC([C@H](CC(C)C)N)=O)[C@@H](C)C)=O

-20°C

12352200