Angelylalkannin [69175-72-0]

TargetMol Chemicals

Angelylalkannin [69175-72-0]

9

Research Use Only

C21H22O6

370.4

Angelylalkannin, a naphthoquinone compound isolated from the roots of Alkanna tinctoria, exhibits significant antiproliferative effects on human colon cancer cells HCT-116 and SW-480. The median inhibitory concentration (IC50) of Angelylalkannin is 4.76 mM for HCT-116 cells and 7.03 mM for SW-480 cells. Similar to alkannin, Angelylalkannin induces cell cycle arrest in the G1 phase and cell apoptosis at concentrations ranging from 1-10 mM.

O=C1C=2C(C(=O)C=C1[C@@H](OC(/C(=C\C)/C)=O)CC=C(C)C)=C(O)C=CC2O

-20°C

12352200