Angiotensin-converting enzyme 2(ACE2)
ACE2-PD_HEK
Product group Molecular Biology
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Overview
- SupplierInVivo Biotech
- Product NameAngiotensin-converting enzyme 2(ACE2)
- Delivery Days Customer5
- CertificationResearch Use Only
- Scientific DescriptionInVivo offers a recombinant form of the peptidase domain (PD) of Angiotensin-converting enzyme 2 (ACE2), which is produced under serum-free conditions in HEK-INV cells (InVivo proprietary optimized; human embryonic kidney, HEK293 cells). ACE2 is the cellular receptor for severe acute respiratory syndrome-coronavirus (SARS-CoV-2). The receptor-binding domain (RBD) of the SARS-CoV-2 Spike (S) protein interacts with the peptidase domain (PD, residues 19-615) of ACE2. The construct contains residues 1-615 of ACE2, comprising the native signal peptide and the peptidase domain (PD). The mature protein is predicted to start with Gln18. The protein includes a C-terminal hexa-histidine-tag and is purified using immobilized metal exchange chromatography (IMAC).
- UNSPSC41116133