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ANGPTL3 (human) ELISA Kit

Research Use Only
AG-45A-0014YEK
AdipoGen Life Sciences
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    ANGPTL3 (human) ELISA Kit
  • Delivery Days Customer
    10
  • Applications
    ELISA
  • Assay Detection Range
    0.156 to 10ng/ml
  • Assay Sensitivity
    75pg/ml
  • Assay Specificity
    Detects human ANGPTL3. Does not cross-react with mouse ANGPTL3, human ANGPTL4, human ANGPTL6, human ANGPTL7 or human ANGPTL2.
  • Certification
    Research Use Only
  • Scientific Description
    ELISA Assay. Detects human ANGPTL3. Does not cross-react with mouse ANGPTL3, human ANGPTL4, human ANGPTL6, human ANGPTL7 or human ANGPTL2. Colorimetric assay. Sample Types: Cell Culture Supernatant, Plasma, Serum. Range: 0.156 to 10ng/ml. Sensitivity: 75pg/ml. Seven proteins containing an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain, both characteristics of angiopoietins, have been identified and therefore designated angiopoietin-like proteins 1-7 (ANGPTL 1-7). ANGPTL3 and ANGPTL6 (Angiopoietin-related growth factor; AGF), among others, function to regulate angiogenesis and also appear to directly regulate lipid, glucose, and energy metabolism. ANGPTL3 plasma levels are increased in a mouse model of diabetes mellitus. - Seven proteins containing an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain, both characteristics of angiopoietins, have been identified and therefore designated angiopoietin-like proteins 1-7 (ANGPTL 1-7). ANGPTL3 and ANGPTL6 (Angiopoietin-related growth factor; AGF), among others, function to regulate angiogenesis and also appear to directly regulate lipid, glucose, and energy metabolism. ANGPTL3 plasma levels are increased in a mouse model of diabetes mellitus.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    41116158

References

  • Exercise training restores the endothelial response to vascular growth factors in patients with stable coronary artery disease: E.B. Beck, et al.; Eur. J. Prev. Cardiol. 19, 412 (2012)
  • Characterization of three kindreds with familial combined hypolipidemia caused by loss-of-function mutations of ANGPTL3: L. Pisciotta, et al.; Circ. Cardiovasc. Gent. 5, 42 (2012)
  • Atypical angiopoietin-like protein that regulates ANGPTL3: F. Quagliarini, et al.; PNAS 109, 19751 (2012)
  • Clinical characteristics and plasma lipids in subjects with familial combined hypolipidemia: a pooled analysis: I. Minicocci, et al.; J. Lipid Res. 54, 3481 (2013)
  • Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation: G. Flehmig, et al.; PLos One 9, e99785 (2014)