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Annonacin

HY-N2877
MedChem Express
CAS Number111035-65-5
Product group Chemicals
Estimated Purity97.0
Molecular Weight596.88
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Annonacin [111035-65-5]
  • Delivery Days Customer
    10
  • CAS Number
    111035-65-5
  • Certification
    Research Use Only
  • Estimated Purity
    97.0
  • Molecular Formula
    C35H64O7
  • Molecular Weight
    596.88
  • Scientific Description
    Annonacin is an acetylgenin that is toxic by inhibiting the pathway of the mitochondrial complex. Annonacin increases tau phosphorylation in R406W+/+ mice. Annonacin acts as an inhibitor of the sodium/potassium and sarcoplasmic reticulum (SERCA) ATPase pumps. Annonacin has significant killing effect on ovarian cancer cell, cervical cancer cell, breast cancer cell, bladder cancer cell and skin cancer cell. Annonacin induces apoptosis through Bax and Caspase-3-related pathways[1][2][3][4].
  • SMILES
    O=C1O[C@@H](C)C=C1C[C@H](O)CCCCC[C@@H](O)CCCC[C@@H](O)[C@@H]2O[C@@H]([C@H](O)CCCCCCCCCCCC)CC2
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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