Annonacin
HY-N2877
Overview
- SupplierMedChem Express
- Product NameAnnonacin [111035-65-5]
- Delivery Days Customer10
- CAS Number111035-65-5
- CertificationResearch Use Only
- Estimated Purity97.0
- Molecular FormulaC35H64O7
- Molecular Weight596.88
- Scientific DescriptionAnnonacin is an acetylgenin that is toxic by inhibiting the pathway of the mitochondrial complex. Annonacin increases tau phosphorylation in R406W+/+ mice. Annonacin acts as an inhibitor of the sodium/potassium and sarcoplasmic reticulum (SERCA) ATPase pumps. Annonacin has significant killing effect on ovarian cancer cell, cervical cancer cell, breast cancer cell, bladder cancer cell and skin cancer cell. Annonacin induces apoptosis through Bax and Caspase-3-related pathways[1][2][3][4].
- SMILESO=C1O[C@@H](C)C=C1C[C@H](O)CCCCC[C@@H](O)CCCC[C@@H](O)[C@@H]2O[C@@H]([C@H](O)CCCCCCCCCCCC)CC2
- Storage Instruction2°C to 8°C
- UNSPSC12352200