Anomalin A [548740-86-9]

AdipoGen Life Sciences

Anomalin A [548740-86-9]

10

548740-86-9

Research Use Only

>97%

C14H10O6

274.1

Antiproliferative agent against selected cancer cell lines. Inhibits protein kinases ALK, ARK5, Aurora-B, AXL, FAK, IGF1-R, MET, PIM1, PLK1, PRK1, SRC, and VEGF-R2 with IC50 values between 0.3 and 75.7microM, most probably contributing to the antiproliferative activity. Shown to inhibit VEGF-A dependent endothelial cells sprouting with IC50 value of 1.8microM corresponding to its in vitro inhibitory activity against VEGF-R2 protein kinase (IC50=0.8microM). Lck (p56lck; lymphocyte specific tyrosine kinase) inhibitor. Antioxidant. DPPH radical scavenger. - Chemical. CAS: 548740-86-9. Formula: C14H10O6. MW: 274.1. Isolated from marine fungus Arthrinium sp. Lck (p56lck; lymphocyte specific tyrosine kinase) inhibitor. Antioxidant. DPPH radical scavenger.

[H]C1=C(O)C(O)=C(C)C2=C1OC1=C(C(O)=CC(O)=C1)C2=O

-20°C,2°C to 8°C

12352200