Anomalin A

Bioss Antibodies

Anomalin A [548740-86-9]

16

Research Use Only

>97%

Antiproliferative agent against selected cancer cell lines. Inhibits protein kinases ALK, ARK5, Aurora-B, AXL, FAK, IGF1-R, MET, PIM1, PLK1, PRK1, SRC, and VEGF-R2 with IC50 values between 0.3 and 75.7microM, most probably contributing to the antiproliferative activity. Shown to inhibit VEGF-A dependent endothelial cells sprouting with IC50 value of 1.8microM corresponding to its in vitro inhibitory activity against VEGF-R2 protein kinase (IC50=0.8microM). Lck (p56lck; lymphocyte specific tyrosine kinase) inhibitor. Antioxidant. DPPH radical scavenger.

-20°C

12352200