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Chemical Structure
Chemical Structure
Chemical Structure

Anthralin

CDX-D0308
Chemodex
CAS Number1143-38-0
Product group Chemicals
Estimated Purity>98%
Molecular Weight226.2
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Overview

  • Supplier
    Chemodex
  • Product Name
    Anthralin [1143-38-0]
  • Delivery Days Customer
    10
  • CAS Number
    1143-38-0
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Warning
  • Molecular Formula
    C14H10O3
  • Molecular Weight
    226.2
  • Scientific Description
    Anthralin is a leukotriene biosynthesis inhibitor. It inhibits LTB4 omega-oxidation and disrupts mitochondria function. Anthralin is used in the treatment of psoriasis, as a fungicide, in the treatment of ringworm infections and in chronic dermatoses. It accumulates in mitochondria where it interferes with the supply of energy to the cell, probably by the oxidation of dithranol releasing free radicals. This impedes DNA replication and so slows the excessive cell division that occurs in psoriatic plaques. Numerous studies have demonstrated anti-proliferative and anti-inflammatory effects of anthralin on psoriatic and normal skin. It is also used as matrix substance for MALDI-MS (matrix-assisted laser desorption ionization MS). - Chemical. CAS: 1143-38-0. Formula: C14H10O3. MW: 226.2. Synthetic. Anthralin is a leukotriene biosynthesis inhibitor. It inhibits LTB4 omega-oxidation and disrupts mitochondria function. Anthralin is used in the treatment of psoriasis, as a fungicide, in the treatment of ringworm infections and in chronic dermatoses. It accumulates in mitochondria where it interferes with the supply of energy to the cell, probably by the oxidation of dithranol releasing free radicals. This impedes DNA replication and so slows the excessive cell division that occurs in psoriatic plaques. Numerous studies have demonstrated anti-proliferative and anti-inflammatory effects of anthralin on psoriatic and normal skin. It is also used as matrix substance for MALDI-MS (matrix-assisted laser desorption ionization MS).
  • SMILES
    OC1=CC=CC2=C1C(=O)C1=C(O)C=CC=C1C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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