Anti-17beta estradiol [17E12E5]

Absolute Antibody

Anti-17beta estradiol [17E12E5]

9

The antibody binds to 17beta estradiol with an ED50 of 76 pg/ml.

The antibody binds specifically to 17beta-estradiol, a mammalian estrogenic steroid hormone which is produced in the ovaries, placenta and testis. In women, the hormone plays an important role in the development of secondary sexual characteristics and maturation of long bones. The hormone is also responsible for the activation of certain oncogenes, and can be involved in the development of breast cancer and cancer of the uterine lining. Anti-estradiol antibodies can be useful in the detection of hormone concentrations in serum samples. This can be used therapeutically to monitor follicular maturation in cases of female infertility, and estradiol secreting tumours.

ImmunoPrecipitation, Western Blot, ELISA, RadioImmunoAssay

Research Use Only

Monoclonal

17E12E5

Rabbit

IgG

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

12352203