Anti-2.4[2.8]2.4-linked Kdo tetrasaccharide [S48-18]

Absolute Antibody

Anti-2.4[2.8]2.4-linked Kdo tetrasaccharide [S48-18]

7

This antibody is specific for 2.4[2.8]2.4-linked Kdo tetrasaccharide. Which is a partial structure of chlamydial lipopolysaccharide (LPS).

An ELISA was performed on neoglycoconjugates using the mouse version of this antibody, it showed the strongest binding to alphaKdo(2 to 4)alphaKdo(2 to 4)alphaKdo and alphaKdo(2 to 4)alphaKdo(2 to 4)alphaKdo(2 to 6)betaGlcNAc. ELISA was also performed on LPS antigens and bacterial antigens using the mouse version of this antibody, it bound most strongly to Chl. psittaci EB and Chl. psittaci LPS (Brade et al, 2000; pmid:11521056). The scFv version of this antibody was used for an ELISA on neoglycoconugates, the antibody bound to 2.4/2.4PS4P and HS4P quite well but bound less well to 2.8/2.4PS4P (Gerstenbruch et al, 2010; pmid:20022906).

ELISA

ELISA

Research Use Only

Monoclonal

S48-18

Rabbit

IgG

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Other Species

Species independent

This antibody was generated by immunizing BALB/c mice with alfaKdo(2→4)alfaKdo(2→4)alfaKdo-BSA.

-20°C,2°C to 8°C

12352203