anti-ABL1/2 phospho (Tyr393 / 439) antibody
ARG51820
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetABL2
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-ABL1/2 phospho (Tyr393 / 439) antibody
- Delivery Days Customer23
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID27
- Target nameABL2
- Target descriptionABL proto-oncogene 2, non-receptor tyrosine kinase
- Target synonymsAbelson tyrosine-protein kinase 2; abelson-related gene protein; ABLL; ARG; c-abl oncogene 2, non-receptor tyrosine kinase; tyrosine-protein kinase ABL2; tyrosine-protein kinase ARG; v-abl Abelson murine leukemia viral oncogene homolog 2
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionRegulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203