Anti-Acetyllysine Rabbit mAb

PTM BIO

Anti-Acetyllysine Rabbit mAb

5

Anti-Acetyllysine Rabbit mAb detects proteins with acetylated lysine residues. This pan antibody recognizes acetylated lysine independent of its surrounding sequences.

ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry Paraffin

WB, IHC-P, IP, ChIP

Antibody

Research Use Only

Monoclonal

PA-070-53

Unconjugated

Rabbit

IgG

The reversible lysine acetylation of histones and non-histone proteins is a crucial post-translational modification that regulates diverse cellular processes, including chromatin dynamics, gene expression, cell cycle progression, apoptosis, differentiation, DNA replication, DNA repair, nuclear import, and neuronal repression. More than 20 acetyltransferases and 18 histone deacetylases (HDACs) have been identified, but the mechanisms governing substrate selection and site specificity of these enzymes remain unclear. Dysregulation of protein acetylation has been implicated in the development of cancers and other diseases, and HDACs have become likely targets for anti-cancer drugs.

Stable for 12 months from date of receipt/reconstitution.

All Species

All

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203