Anti-ACK1

Applied Biological Materials

Anti-ACK1

9

Not tested with other proteins

Western Blot, ELISA

Research Use Only

Polyclonal

Rabbit

IgG

This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinic GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.

Human, Mouse

-20°C,2°C to 8°C

12352203