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anti-ACMSD antibody

Research Use Only
ARG66310
Arigo Biolaboratories
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetACMSD
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-ACMSD antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.8 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID130013
  • Target name
    ACMSD
  • Target description
    aminocarboxymuconate semialdehyde decarboxylase
  • Target synonyms
    2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; picolinate carboxylase
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM, Oct 2004]
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203