anti-ACTL6A / BAF53A antibody

Arigo Biolaboratories

anti-ACTL6A / BAF53A antibody

23

Western Blot

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

ACTL6A

actin like 6A

53 kDa BRG1-associated factor A; actin-like protein 6A; actin-related protein 4; actin-related protein Baf53a; ACTL6; Arp4; arpNbeta; ARPN-BETA; BAF complex 53 kDa subunit; BAF53; BAF53A; BRG1-associated factor 53A; hArpN beta; INO80 complex subunit K; INO80K; SMARCN1

Goat

IgG

This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008]

Bovine, Canine, Human, Mouse, Porcine, Rat

-20°C

12352203