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anti-ACVR1C / ALK7 antibody

Research Use Only
ARG66527
Arigo Biolaboratories
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetACVR1C
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-ACVR1C / ALK7 antibody
  • Delivery Days Customer
    23
  • Applications
    ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID130399
  • Target name
    ACVR1C
  • Target description
    activin A receptor type 1C
  • Target synonyms
    activin A receptor, type IC; activin receptor type IC; activin receptor type-1C; activin receptor-like kinase 7; ACTR-IC; ACVRLK7; ALK7; ALK-7
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203