Anti-ADAMts13 [1-420 scFv]

Absolute Antibody

Anti-ADAMts13 [1-420 scFv]

7

Mice transfected with the scFv show ADAMTS13 inhibition and accumulation of unprocessed UL-VWF (ultralarge VWF) multimers. 1-420 mediates inhibition by binding to the same spacer domain loop domain segments required for ADAMTS13 binding to VWF. Please note that this antibody is subject to a pending patent application by the The Trustees Of The University Of Pennsylvania (WO2016164468 A2).

Neutralisation/Blocking

Inhibit

Research Use Only

A disintegrin and metalloproteinase with thrombospondin motifs 13

This full-length, chimeric mouse antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

12352203