anti-AKAP12 / Gravin antibody

Arigo Biolaboratories

anti-AKAP12 / Gravin antibody

23

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

Akap12

A-kinase anchoring protein 12

A kinase (PRKA) anchor protein (gravin) 12; A kinase (PRKA) anchor protein 12; AKAP-12; AKAP12A; AKAP12B; AKAP12G; A-kinase anchor protein 12; SSeCKS, Gravin, AKAP250

Sheep

IgG

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Rat

-20°C

12352203