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anti-AKAP12 / Gravin antibody

Research Use Only
ARG11086
Arigo Biolaboratories
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityRat
TargetAkap12
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-AKAP12 / Gravin antibody
  • Delivery Days Customer
    23
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID83425
  • Target name
    Akap12
  • Target description
    A-kinase anchoring protein 12
  • Target synonyms
    A kinase (PRKA) anchor protein (gravin) 12; A kinase (PRKA) anchor protein 12; AKAP-12; AKAP12A; AKAP12B; AKAP12G; A-kinase anchor protein 12; SSeCKS, Gravin, AKAP250
  • Host
    Sheep
  • Isotype
    IgG
  • Scientific Description
    The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Reactivity
    Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203